Using pf
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Plasmodium falciparum (Pf) whole-organism sporozoite vaccines have been shown to provide significant protection against controlled human malaria infection (CHMI) in clinical trials. Initial CHMI studies showed significantly higher durable protection against homologous than heterologous strains, suggesting the presence of strain-specific vaccine-induced protection.
17p vibransone 28-03-2024 3 2 Download
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To investigate the expression and prognostic value of c-Jun in hypopharyngeal squamous cell carcinoma (HPSCC). Methods: A retrospective study was performed on a cohort of 99 HPSCC patients. The expression of c-Jun and phosphorylated-c-Jun (p-c-Jun) was evaluated via immunohistochemistry (IHC) staining. Overall survival (OS) and progression-free survival (PFS) were assessed using Kaplan–Meier method and multivariate Cox regression analysis.
11p vialfrednobel 23-12-2023 5 3 Download
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Overall survival (OS) is the gold standard to assess novel therapeutics to treat cancer. However, to identify early efficacy and speed up drug approval, trials have used progression-free survival (PFS) as a surrogate endpoint (SE). Herein, we aimed to examine if PFS could function as an OS surrogate in advanced Esophageal Squamous Cell Carcinoma (ESCC) treated with first-line immunochemotherapy.
13p vischultz 20-10-2023 2 1 Download
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Glioblastoma (GBM) is the most malignant primary tumor in the brain, with poor prognosis and limited effective therapies. Although Bevacizumab (BEV) has shown promise in extending progressionfree survival (PFS) treating GBM, there is no evidence for its ability to prolong overall survival (OS)
23p visharma 20-10-2023 5 2 Download
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Carbon microspheres with a uniform size of about 170 μm were prepared in a simple co-flow microfluidic device using solvent extraction method. An ethanol solution of colloidal silica and phenol formaldehyde (PF) resol was used as the dispersion phase, and a mixture of hexane and diisopropylamine was used as the continuous phase. The droplets of PF resol resin/silica were generated in the continuous phase.
7p vironald 15-12-2022 6 3 Download
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Bullet-resistance and weight are important features of anti ballistic materials. Kevlar fibers are the widest reinforcement material for military and civil systems due to their excellent impact resistance and high strength-to-weight ratio. Kevlar fibre based composites are used for designing personal helmets and body armor to effectively stop both fragmentation and bullets.
8p vispyker 14-11-2022 13 2 Download
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Due to the fast-growing relapsed/refractory multiple myeloma (RRMM) treatment landscape, a comparison of all the available treatments was warranted. For clinical practice it is important to consider both immediate effects such as response quality and prolonged benefits such as progression-free survival (PFS) in a meta-analysis. The objective of this study was to assess the impact of the choice of outcome on the treatment rankings in RRMM.
12p visusanwojcicki 28-06-2022 8 2 Download
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The Pittsburgh Fatigability Scale (PFS) was developed to capture fatigue and demand in a single tool, filling a gap that no validated questionnaire existed to measure perceived fatigability. Since fatigability is a more sensitive measure of a person’s susceptibility to fatigue, we validated the simplified-Chinese version of the PFS among Chinese community-dwelling older adults.
8p vinobelprisen 26-03-2022 17 4 Download
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Cationic starch (CS) was prepared by using epichlorohydrin (EPI) and 3-chloro-2-hydroxypropyltrimethylammonium chloride (CHPTMA) and ionic liquids (ILs) having different anionic groups [1-butyl-3-methyl imidazolium tetrafluoroborate (BMI+BF−4), 1-butyl-3-methyl imidazolium bromide (BMI+Br−), 1-butyl-3-methyl imidazolium hexafluorophosphate (BMI+PF−6), and 1-butyl-3-methyl imidazolium bis-[(trifluoromethyl)sulfonyl]imide (BMI+[(TF)2N]−)] were impregnated onto CS. Thorium(IV) ions were preconcentrated by using IL impregnated CS.
9p langthannam 29-12-2021 2 0 Download
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Aim to establish the inhibitors of programmed cell death protein 1 (PD-1) as second-line therapy for advanced esophageal squamous cell carcinoma (ESCC). Overall survival (OS), progression-free survival (PFS), objective response rate (ORR), disease control rate (DCR), and treatment-related adverse events (TRAEs) were synthesized using STATA.
10p vimahuateng 26-11-2021 7 1 Download
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Adenoid cystic carcinoma is a rare form of head and neck cancer with a slow, but aggressive growth pattern which remains a challenge for local tumor control. Based on phase II data, radiation treatment using partially high LET radiation results in a prolonged PFS and OS.
8p vimahuateng 26-11-2021 3 1 Download
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Several studies have verified body fat distribution in association with pulmonary function (PF), mainly waist circumference, but few have used measures able to distinguish abdominal fat compartments. The present study aims to verify the association of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) with PF measures.
8p vimaine2711 26-03-2021 4 1 Download
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The lifetime implants is a key parameter that the surgeon should take into account at the time of the primary total hip arthroplasty (THA). The aim of this study was a clinical and radiographical evaluation of the Delta PF-FIT (LimaCorporate, Italy) THA system with ceramic-on-ceramic articulations.
7p vimariana2711 22-12-2020 5 1 Download
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Field experiment was conducted for the management of root rot of patchouli (Fusarium solani) by using fungicide (Carbendazim), commercial bio-formulation Biofor-pf-2 (Trichoderma harzianum and Pseudomonas fluroenscens) and oilcake (Mustard oil cake) alone and its combinations.
13p caygaocaolon8 07-11-2020 5 0 Download
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Supporting health care sector decisions using time-dependent endpoints (TDEs) such as time to progression (TTP), progression-free survival (PFS), and event-free survival (EFS) remains controversial. This study estimated the quantitative relationship between median TDE and median overall survival (OS) in multiple myeloma (MM) patients.
12p vijisoo2711 29-09-2020 14 1 Download
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We describe the clinical benefit of immune checkpoint inhibitors using the European Society for Medical Oncology Magnitude of Clinical Benefit Scale (ESMO-MCBS) and ASCO VF. Methods: We identify all approved indications of immune checkpoint inhibitors based on RCTs between January 1, 2011 and September 30, 2018 by FDA. Information including medians and HR of OS (PFS or DFS) and 95% CI, grade 3 or 4 toxicities in each arm, QOL data, survival probability at fixed time were extracted.
11p vialabama2711 21-09-2020 13 1 Download
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The objective of this work was to establish the compatibility under laboratory conditions, between three fungicides (Cuproflow 37.7 % SC, Yaba M GD 66 and Mancozeb 80 % WP) approved and regularly used to control early blight in Cuba and the biocontrol agents Trichoderma asperellum (strain Ta. 85) and Pseudomonas protegens (Pf-5).
12p nguaconbaynhay7 15-08-2020 12 1 Download
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Glioblastoma relapses in the vast majority of cases within 1 year. Maximum safe resection of the recurrent glioblastoma can be offered in some cases. Re-irradiation has been established for the treatment of recurrent glioblastoma, too. In both cases, adjuvant treatment, mostly using temozolomide, can improve PFS and OS after these interventions.
5p vibaku2711 22-07-2020 12 1 Download
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The human population continues to grow steadily with the shrinking resources being used for agricultural production situates great challenge against Indian agricultural system to attain food and environmental security. To counter these twin challenges in the country there is urgent need of application of modern Hi-tech technologies for enhancing the productivity and sustainability of the rice-wheat system for long term on scientific basis. Precision farming (PF) looks a win-win technology towards improving the capability of agricultural land to produce crops on sustainable basis.
10p chauchaungayxua6 26-06-2020 10 0 Download
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The objective of this work was to establish the quantitative relationship between Lanreotide Autogel® (LAN) on serum chromogranin A (CgA) and progression-free survival (PFS) in patients with nonfunctioning gastroenteropancreatic neuroendocrine tumors (GEP-NETs) through an integrated pharmacokinetic/pharmacodynamic (PK/PD) model. In CLARINET, a phase III, randomized, doubleblind, placebo-controlled study, 204 patients received deep subcutaneous injections of LAN 120 mg (n = 101) or placebo (n = 103) every 4 weeks for 96 weeks.
10p caothientrangnguyen 09-05-2020 15 0 Download