A biomechanical, microcomputertomographic and histological analysis of the influence of diclofenac and prednisolone on fracture healing in vivo

Non-steroidal anti-inflammatory drugs (NSAIDs) have long been suspected of negatively affecting fracture healing, although numerous disputes still exist and little data are available regarding diclofenac. Glucocorticoids interfere in this process over a similar and even broader mechanism of action.