A high frequency of CD8+ CD28– T-suppressor cells contributes to maintaining stable graft function and reducing immunosuppressant dosage after liver transplantation

CD8+CD28-T cells (CD8Ts) exert immunosuppressive effects in various autoimmune diseases. The current study was designed to investigate the role of defects in CD8Ts in liver transplantation (LT). The proportion of CD8Ts in peripheral blood was determined by flow cytometry.