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A phase II study of the PI3K inhibitor copanlisib in combination with the antiCD20 monoclonal antibody rituximab for patients with marginal zone lymphoma: Treatment rationale and protocol design of the COUP-1 trial
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Advanced stage marginal zone lymphoma (MZL) is an incurable indolent B-cell lymphoma, for which a wide variety of treatments ranging from single agent rituximab to more dose intense immunochemotherapy exists.
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