Anesthesia management of patients undergoing hyperthermic isolated limb perfusion with melphalan for melanoma treatment: An analysis of 17 cases

Hyperthermic isolated limb perfusion (HILP) is used for patients with intractable or extensive in-transit metastatic melanoma of the limb to deliver high concentrations of cytotoxic agents to the affected limb and offers a treatment option in a disease stage with a poor prognosis when no treatment is given.