Antimicrobial activity of a novel secondary metabolite from streptomyces sp. and molecular docking studies against bacterial leaf blight pathogen of rice

The metabolite 2-(1,1-diallyl-but-3-enyl)-5-nonyl-phenol isolated from Streptomyces sp. TC1 exhibited antimicrobial activity against bacterial leaf blight pathogen Xanthomonas oryzae pv. oryzae (Xoo). The in vitro antimicrobial activity was found to be between 1.8-2.5 cm in agar well diffusion assay against the tested Xoo isolates and 200 µg/ml in terms of minimum inhibitory concentration. The isolated compound showed well binding with the virulence proteins of Xoo by producing a better docking score in molecular docking studies.