intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo khoa học: A comparative analysis of the time-dependent antiproliferative effects of daunorubicin and WP631

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:7

40
lượt xem
5
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

Jurkat T lymphocytes were treated with daunorubicin and WP631, a daunorubicin-based DNAbinding agent, in experiments aimed to analyze cellular uptake of these drugs and their effect on cell viability. WP631 was taken up more slowly than daunorubicin, but laser confocal microscopy and spectrofluorometricquantificationshowed that thedrug accumulated in the cells. Despite the slow uptake rate, the antiproliferative capacity of WP631 (measured as IC50after a 72-h continuous treatment) was greater than that of daunorubicin. The propensities of daunorubicinandWP631 to promote apoptosis were compared....

Chủ đề:
Lưu

Nội dung Text: Báo cáo khoa học: A comparative analysis of the time-dependent antiproliferative effects of daunorubicin and WP631

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
2=>2