Báo cáo khoa học: Accumulation of mitochondrial DNA damage and bioenergetic dysfunction in CSB defective cells
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Cockayne syndrome (CS) is a complex, progressive disease that involves neurological and developmental impairment and premature aging. The majority of CS patients have mutations in theCSBgene. The CSB protein is involved in multiple DNA repair pathways and CSBmutated cells are sensitive to a broad spectrum of genotoxic agents.
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