Báo cáo khoa học: Analysis and biological relevance of advanced glycation end-products of DNA in eukaryotic cells
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Advanced glycation end-products (AGEs) of DNA are formed spontane-ously by the reaction of carbonyl compounds such as sugars, methylglyoxal or dihydroxyacetonein vitro andin vivo. Little is known, however, about the biological consequences of DNA AGEs. In this study, a method was developed to determine the parameters that promote DNA glycation in cultured cells.
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