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Báo cáo khoa học: Characterization of a eukaryotic type serine/threonine protein kinase and protein phosphatase of Streptococcus pneumoniae and identification of kinase substrates
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Searching the genome sequence ofStreptococcus pneumoniaerevealed the presence of a single Ser⁄Thr protein kinase genestkP linked to protein phosphatasephpP. Biochemical studies performed with recombinant StkP suggest that this protein is a functional eukaryotic-type Ser⁄Thr protein kinase.In vitrokinase assays and Western blots ofS. pneumoniaesubcellu-lar fractions revealed that StkP is a membrane protein.
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