
Báo cáo khoa học: Critical roles of conserved carboxylic acid residues in pigeon cytosolic NADP+-dependent malic enzyme
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Malic enzyme catalyses the reduction of NADP+ to NADPH and the decarboxylation ofl-malate to pyruvate through a general acid⁄base mech-anism. Previous kinetic and structural studies differ in their interpretation of the amino acids responsible for the general acid⁄base mechanism.
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