Báo cáo khoa học: Diterpene production in Mycobacterium tuberculosis Lisa Prach1, James Kirby2, Jay D. Keasling2,3,4 and Tom Alber1

Diterpenes are a structurally diverse class of molecules common in plants, although they are very rarely found in bacteria. We report the identifica-tion in Mycobacterium tuberculosis(Mtb) of three diterpenes proposed to promote phagolysosome maturation arrest. MS analysis reveals that these diterpenes are novel compounds not previously identified in other organ-isms.