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Báo cáo khoa học: Epidermal growth factor receptor ligands as new extracellular targets for the metastasis-promoting S100A4 protein
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The function of S100A4, a member of the calcium-binding S100 protein family, has been associated with tumor invasion and metastasis. Although an essential pro-metastatic role of extracellular S100A4 in tumor progres-sion has been demonstrated, the identification of the precise underlying mechanisms and protein partners (receptors) has remained elusive.
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