Báo cáo khoa học: Evolutionary and experimental analyses of inorganic phosphate transporter PiT family reveals two related signature sequences harboring highly conserved aspartic acids critical for sodium-dependent phosphate transport function of human PiT2
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The mammalian members of the inorganic phosphate (Pi ) transporter (PiT) family, the type III sodium-dependent phosphate (NaP i) transporters PiT1 and PiT2, have been assigned housekeeping Pi transport functions and are suggested to be involved in chondroblastic and osteoblastic mineralization and ectopic calcification.
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