Báo cáo khoa học: Identification of ERRa as a specific partner of PGC-1a for the activation of PDK4 gene expression in muscle
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Pyruvate dehydrogenase kinase 4 (PDK4) is a key regulatory enzyme involved in switching the energy source from glucose to fatty acids in response to physiological conditions. Transcription of the PDK4gene is activated by fasting or by the administration of a PPARaligand in a tis-sue-specific manner.
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