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Báo cáo khoa học: Inhibition of aryl acid adenylation domains involved in bacterial siderophore synthesis
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Aryl acid adenylation domains are the initial enzymes for aryl-capping of catecholic siderophores in a plethora of microorganisms. In order to over-come the problem of iron acquisition in host organisms, siderophore bio-synthesis is decisive for virulence development in numerous important human and animal pathogens.
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