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Báo cáo khoa học: Interaction with model membranes and pore formation by human stefin B – studying the native and prefibrillar states
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Human stefin B, from the family of cystatins, is used as a model amyloido-genic protein in studies of the mechanism of amyloid fibril formation and related cytotoxicity. Interaction of the protein’s prefibrillar oligo-mers⁄aggregates with predominantly acidic phospholipid membranes is known to correlate with cellular toxicity.
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