Báo cáo khoa học: Membrane compartments and purinergic signalling: the purinome, a complex interplay among ligands, degrading enzymes, receptors and transporters
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Receptors should be properly analysed in view of the microenvironment in which they are embedded. Therefore, the concept of ‘receptosome’ was for-mulated to the complex interactions taking place between receptors and other proteins at the plasma membrane level, and to explain very heteroge-neous or divergent cellular responses to common epigenetic factors and modifications to the extracellular environment.
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