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Báo cáo khoa học: Molecular organization and force-generating mechanism of dynein
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Dynein, which is a minus-end-directed microtubule motor, is crucial to a range of cellular processes. The mass of its motor domain is about 10 times that of kinesin, the other microtubule motor. Its large size and the diffi-culty of expressing and purifying mutants have hampered progress in dynein research.
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