Báo cáo khoa học: Retention of the duplicated cellular retinoic acid-binding protein 1 genes (crabp1a and crabp1b) in the zebrafish genome by subfunctionalization of tissue-specific expression
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The cellular retinoic acid-binding protein type I (CRABPI) is encoded by a single gene in mammals. We have characterized twocrabp1genes in zebra-fish, designatedcrabp1a and crabp1b. These twocrabp1 genes share the same gene structure as the mammalianCRABP1genes and encode proteins that show the highest amino acid sequence identity to mammalian CRAB-PIs. The zebrafishcrabp1aandcrabp1bwere assigned to linkage groups 25 and 7, respectively.
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