Báo cáo khoa học: Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms

Talins are large adaptor proteins that link the integrin family of adhesion molecules to F-actin. In vertebrates, there are two talin genes.Talin 1is essential for integrin-mediated cell adhesion; the role oftalin 2 is unclear. Here we report a detailed analysis of mammaliantalin 2.