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Báo cáo khoa học: The complex of the insect LDL receptor homolog, lipophorin receptor, LpR, and its lipoprotein ligand does not dissociate under endosomal conditions

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:16

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The insect low-density lipoprotein (LDL) receptor (LDLR) homolog, lipo-phorin receptor (LpR), mediates endocytic uptake of the single insect lipo-protein, high-density lipophorin (HDLp), which is structurally related to LDL. However, in contrast to the fate of LDL, which is endocytosed by LDLR, we previously demonstrated that after endocytosis, HDLp is sorted to the endocytic recycling compartment and recycled for resecretion in a transferrin-like manner.

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Nội dung Text: Báo cáo khoa học: The complex of the insect LDL receptor homolog, lipophorin receptor, LpR, and its lipoprotein ligand does not dissociate under endosomal conditions

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