Báo cáo khoa học: The miRNA-192 ⁄194 cluster regulates the Period gene family and the circadian clock
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Several biological functions in mammals are regulated in a circadian fash-ion. The molecular mechanisms orchestrating these circadian rhythms have been unravelled. The biological clock, with its core transcriptional unit Bmal1⁄CLOCK, is composed of several self-sustaining feedback loops. In this study, we describe another mechanism impinging on the core compo-nents of the circadian clock.
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