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Báo cáo khoa học: The monopartite nuclear localization signal of autoimmune regulator mediates its nuclear import and interaction with multiple importin a molecules
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Autoimmune regulator (AIRE) is a transcriptional regulator involved in establishing immunological self-tolerance. Mutations in theAIREgene lead to the development of the autosomal, recessively inherited, organ-specific autoimmune disease, autoimmune polyendocrinopathy candidiasis ectoder-mal dystrophy (APECED).
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