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Báo cáo khoa học: The plasminogen activator inhibitor 2 transcript is destabilized via a multi-component 3¢ UTR localized adenylate and uridylate-rich instability element in an analogous manner to cytokines and oncogenes

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:14

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Plasminogen activator inhibitor type 2 (PAI-2; SERPINB2)is a highly-regulated gene that is subject to both transcriptional and post-transcrip-tional control. For the latter case, inherent PAI-2 mRNA instability was previously shown to require a nonameric adenylate-uridylate element in the 3¢ UTR.

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Nội dung Text: Báo cáo khoa học: The plasminogen activator inhibitor 2 transcript is destabilized via a multi-component 3¢ UTR localized adenylate and uridylate-rich instability element in an analogous manner to cytokines and oncogenes

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