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Báo cáo Y học: Prediction of temporal gene expression Metabolic optimization by re-distribution of enzyme activities

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:8

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Acomputational approach is used to analyse temporal gene expression in the context of metabolic regulation. It is based on the assumption that cells developed optimal adaptation strategies to changing environmental conditions. Time-dependent enzyme profiles are calculatedwhichoptimize the function of a metabolic pathway under the constraint of limited total enzymeamount.For linearmodel pathways it is shown thatwave-like enzyme profiles are optimal for a rapid substrate turnover.

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Nội dung Text: Báo cáo Y học: Prediction of temporal gene expression Metabolic optimization by re-distribution of enzyme activities

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