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Báo cáo Y học: The role of arginine residues in substrate binding and catalysis by deacetoxycephalosporin C synthase
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Oxford Centre for Molecular Sciences and the Dyson Perrins Laboratory, Oxford, UK; 2Department of Biochemistry, National Defence Medical Centre, Taipei, Taiwan; 3Department of Pharmacy and Pharmacology, The University of Bath, UK Deacetoxycephalosporin C synthase (DAOCS) catalyses the oxidative ring expansion of penicillin N, the committed step in the biosynthesis of cephamycin C by Streptomyces clavuligerus.
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