Chapter 039. Nausea, Vomiting, and Indigestion (Part 6)
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Gastric Motor Dysfunction Disturbed gastric motility is purported to cause acid reflux in some cases of indigestion. Delayed gastric emptying is also found in 25–50% of functional dyspeptics. The relation of these defects to symptom induction is uncertain; many studies show poor correlation between symptom severity and the degree of motor dysfunction. Impaired gastric fundus relaxation after eating may underlie selected dyspeptic symptoms like bloating, nausea, and early satiety. Visceral Afferent Hypersensitivity Disturbed gastric sensory function is proposed as a pathogenic factor in functional dyspepsia. Visceral afferent hypersensitivity was first demonstrated in patients with irritable bowel syndrome who had heightened perception of rectal...
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