Chapter 054. Skin Manifestations of Internal Disease (Part 18)

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Papulonodular Skin Lesions (Table 54-15) In the papulonodular diseases, the lesions are elevated above the surface of the skin and may coalesce to form plaques. The location, consistency, and color of the lesions are the keys to their diagnosis; this section is organized on the basis of color. Table 54-15 Papulonodular Skin Lesions According to Color Groups I. White A. Calcinosis cutis II. Skin-colored A. Rheumatoid nodules B. Neurofibromas (von Recklinghausen's disease) C. Angiofibromas (tuberous sclerosis, MEN syndrome, type 1) D. Neuromas (MEN syndrome, type 2b) E. Adnexal tumors 1. Basal cell carcinomas (nevoid basal cell carcinoma syndrome) 2. Tricholemmomas (Cowden disease) F. Osteomas (Gardner syndrome) G. Primary cutaneous disorders 1. Epidermal inclusion...

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Chapter 054. Skin Manifestations of Internal Disease (Part 18) Papulonodular Skin Lesions (Table 54-15) In the papulonodular diseases, the lesions are elevated above the surface of the skin and may coalesce to form plaques. The location, consistency, and color of the lesions are the keys to their diagnosis; this section is organized on the basis of color. Table 54-15 Papulonodular Skin Lesions According to Color Groups I. White A. Calcinosis cutis
II. Skin-colored A. Rheumatoid nodules B. Neurofibromas (von Recklinghausen's disease) C. Angiofibromas (tuberous sclerosis, MEN syndrome, type 1) D. Neuromas (MEN syndrome, type 2b) E. Adnexal tumors 1. Basal cell carcinomas (nevoid basal cell carcinoma syndrome) 2. Tricholemmomas (Cowden disease) F. Osteomas (Gardner syndrome) G. Primary cutaneous disorders 1. Epidermal inclusion cysts
2. Lipomas III. Pink/translucenta A. Amyloidosis B. Papular mucinosis IV. Yellow A. Xanthomas B. Tophi C. Necrobiosis lipoidica D. Pseudoxanthoma elasticum E. Sebaceous adenomas (Torre syndrome) V. Reda
A. Papules 1. Angiokeratomas (Fabry disease) 2. Bacillary angiomatosis (primarily in AIDS) B. Papules/plaques 1. Cutaneous lupus 2. Lymphoma cutis 3. Leukemia cutis C. Nodules 1. Panniculitis 2. Cutaneous polyarteritis nodosa 3. Systemic vasculitis
D. Primary cutaneous disorders 1. Arthropod bites 2. Cherry hemangiomas 3. Infections, e.g., erysipelas, sporotrichosis 4. Polymorphous light eruption 5. Lymphocytoma cutis (pseudolymphoma) VI. Red-browna A. Sarcoidosis B. Sweet's syndrome C. Urticaria pigmentosa D. Erythema elevatum diutinum (chronic leukocytoclastic vasculitis) E. Lupus vulgaris
VII. Bluea A. Venous malformations (blue rubber bleb syndrome) B. Primary cutaneous disorders 1. Venous lake 2. Blue nevus VIII. Violaceous A. Lupus pernio (sarcoidosis) B. Lymphoma cutis C. Cutaneous lupus IX. Purple A. Kaposi's sarcoma
B. Angiosarcoma C. Palpable purpura X. Brown-blackb XI. Any color A. Metastases a May have darker hue in more darkly pigmented individuals. b See also "Hyperpigmentation." Note: MEN, multiple endocrine neoplasia.