Characterization of crilin and nanocurcumin’s synergistic effect on treatment for 7.12 dimethylbenz[a]anthracene (DMBA) induced breast cancer mice

In this study, we established the mouse model of breast cancer induced by DMBA and evaluated the effectiveness of the combination of crilin and nanocurcumin in treatment of breast cancer. After a 12-week coadministration of crilin and nanocurcumin, the DMBA-induced mice’s body weight and the number of erythrocytes and leukocytes in their blood reversed. Furthermore, the synergistic effect of crilin and nanocucumin on reduction in the tumor volume was proven.