Chemical constituents and cytotoxicity of Lepidotrigona ventralis propolis

From propolis of Lepidotrigona ventralis stingless bee collected in Tuyen Quang province, eight compounds were isolated and determined as lantanolic acid, moronic acid, (+)-eudesmin, (+)-yangambin, (+)-syringaresinol, (+)-pinoresinol, dihydroconiferyl alcohol and vanillin using NMR and MS spectral data. Compounds 1 and 2 showed significant cytotoxicity against HepG-2 cancer cell line with IC50 values of 25.84±0.48 and 39.92±1.14 ug/mL, respectively.