Cisplatin sensitivity is enhanced in non-small cell lung cancer cells by regulating epithelialmesenchymal transition through inhibition of eukaryotic translation initiation factor 5A2

Epithelial-mesenchymal transition (EMT) has been believed to be related with chemotherapy resistance in non-small cell lung cancer (NSCLC). Recent studies have suggested eIF5A-2 may function as a proliferation-related oncogene in tumorigenic processes.