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Clustering of circular consensus sequences: Accurate error correction and assembly of single molecule real-time reads from multiplexed amplicon libraries
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Targeted resequencing with high-throughput sequencing (HTS) platforms can be used to efficiently interrogate the genomes of large numbers of individuals. A critical issue for research and applications using HTS data, especially from long-read platforms, is error in base calling arising from technological limits and bioinformatic algorithms.
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