Design, synthesis and antimicrobial evaluation of pyrimidin-2-ol/thiol/amine analogues

Pyrimidine is an aromatic heterocyclic moiety containing nitrogen atomat 1st and 3rd positions and play an important role to forms the central core for different necessity of biological active compounds, from this facts, we have designed and synthesized a new class of pyrimidin-2-ol/thiol/amine derivatives and screened for its in vitro antimicrobial activity.