Dickkopf-4 is frequently overexpressed in epithelial ovarian carcinoma and promotes tumor invasion

Dickkopf-4 (DKK4), a member of DKK family, appears to be a divergent protein. It remained multibiological functions in carcinogenesis. The effect of DKK4 on the ovarian cancer cells remains unclear. This study detected the clinical significance of DKK4 in epithelial ovarian cancer (EOC) patients and its role in invasion.