Ebook Heteroaromatic lipoxin A4 analogues: Synthesis and biological evaluation

In ebook "Heteroaromatic lipoxin A4 analogues: Synthesis and biological evaluation" Colm Duffy reviews the chemistry and biology of stable lipoxin analogues. Colm has prepared for the first time ever a pyridine-containing LXA4 analogue in enantiomerically pure form. Biological evaluation determined that both epimers at the benzylic position suppress key cytokines known to be involved in inflammatory disease, with the (R)-epimer proving most efficacious.