Ebook Self and nonself

Ebook "Self and nonself" focuses on the origin of the immune response during the development of multicellularity (Chapters 1-4). Bacteria have developed defense systems against viruses and conversely, viruses have devised escape mechanisms that allow infection. Most of the archaea and numerous bacteria possess an elaborate system of adaptive immunity known as the CRISPR-Cas, that confers resistance to mobile genetic elements.