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Effect of exercise training on skeletal muscle SIRT1 and PGC-1α expression levels in rats of different age
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The protein deacetylase sirtuin 1 (SIRT1) and activate peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) pathway drives the muscular fiber-type switching, and can directly regulate the biophysiological functions of skeletal muscle.
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