Ex vivo permeation study of nanostructured dosage form containing mango seed kernel extract using franz cell

Mango seeds (Mangiferin indica L.) have the ability to inhibit P. acnes, S. aureus, and E. coli bacteria and inhibit inflammation, potentially for transdermal therapeutic dosage forms. The nano-emulsion dosage forms were prepared based on the SNEDDS system with nano-oil droplets containing mango seed extract. These dosage forms contributed to carrying the active ingredient deeply into the impact site, bringing the highest efficiency, but this needs to be proven.