Genome-wide evolutionary and functional analysis of the Equine Repetitive Element 1: An insertion in the myostatin promoter affects gene expression

In mammals, an important source of genomic variation is insertion polymorphism of retrotransposons. These may acquire a functional role when inserted inside genes or in their proximity. The aim of this work was to carry out a genome wide analysis of ERE1 retrotransposons in the horse and to analyze insertion polymorphism in relation to evolution and function.