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Immune response associated with Toll-like receptor 4 signaling pathway leads to steroid-induced femoral head osteonecrosis
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Femoral head osteonecrosis is frequently observed in patients treated with excessive corticosteroids. The objective of the current study was to establish a rat model to investigate the disruption of immune response in steroid-induced femoral head osteonecrosis via Toll-like receptor 4 (TLR4) signaling pathway.
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