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In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors

Chia sẻ: ViJiraiya2711 ViJiraiya2711 | Ngày: | Loại File: PDF | Số trang:13

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Xanthine oxidase is an important enzyme of purine catabolism pathway and has been associated directly in pathogenesis of gout and indirectly in many pathological conditions like cancer, diabetes and metabolic syndrome. In this research rutin, a bioactive flavonoid was explored to determine the capability of itself and its derivatives to inhibit xanthine oxidase.

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Nội dung Text: In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors

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