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Integrated genomic analysis of biological gene sets with applications in lung cancer prognosis

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Burgeoning interest in integrative analyses has produced a rise in studies which incorporate data from multiple genomic platforms. Literature for conducting formal hypothesis testing on an integrative gene set level is considerably sparse. This paper is biologically motivated by our interest in the joint effects of epigenetic methylation loci and their associated mRNA gene expressions on lung cancer survival status.

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Nội dung Text: Integrated genomic analysis of biological gene sets with applications in lung cancer prognosis

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