Gene expression

This review explores recent ML advancements in assessing corrosion in RC structures. Various algorithms, such as Artificial Neural Networks (ANNs), Gene Expression Programming (GEP), Extreme Gradient Boosting (XGBoost), Support Vector Machine (SVM) and Ensemble Learning, have shown potential in estimating corrosion processes, predicting material properties, and evaluating structural durability.

7p vibenya 31-12-2024 5 2   Download

Phosphoinositide-specific phospholipase C (PI-PLC) has been known as one of the key enzymes that involved in the phospholipid hydrolysis. However, the PI-PLC family in cassava has not been fully recorded. In this study, a comprehensive analysis of the PI-PLC family in cassava assembly has been performed based on various bioinformatics tools.

9p viprimi 16-12-2024 3 1   Download

Studies on nanoparticle-protein interaction have also not been studied. This would give information on ratio influence on the structural alteration of EGCg in EGCg-AuNPs and its functionality in vivo. Herein, the optimisation of EGCg-AuNPs will be determined with a large pool of stoichiometric synthesises of gold and EGCg. These optimised EGCg-AuNPs would then be studied with bovine serum albumin (BSA) for protein interactions, binding and thermodynamics.

177p runthenight07 01-03-2023 11 3   Download

Research objectives: Express GmCHI1A genes in transgenic soybean and create GmCHI1A transgenic soybean lines with higher isoflavone content than non-transgenic control plants.

27p hobbsandshaw 09-06-2021 16 4   Download

Do the following: Study on some histopathological features of prostate carcinoma at Military Hospital 103 according to the 2004 WHO classification. Determine the expression of some immunological markers and methylation status of the RASSF1A gene and compare with some histopathological features in prostate carcinoma.

29p petsematary 02-06-2021 21 3   Download

Analysis of mutation and protein expression of EGFR in patients with lung adenocarcinoma; investigation the hypermethylation frequency of EGFR, BRCA1, MGMT, MLH1, RASSF1A and correlation of the methylation between these genes with mutations and protein expression of EGFR.

27p capheviahe26 25-01-2021 20 4   Download

Detection and screening of genes related to biosynthesis of substances with protease inhibitory activity from microorganisms associated with sponge collected from the Mien trung sea of Vietnam by metagenomics method. Then, selective gene, expression of in vitro and determination of activity of the expressed protein.

27p capheviahe26 25-01-2021 19 4   Download

Assessed the level of mRNA expression of CIZ1b, VEGF, EGFR mutations and the rate of Merkel cell infection in patients with non-small cell lung cancer. Assessed the level of mRNA expression of CIZ1b, VEGF, EGFR mutations and the rate of Merkel cell infection in patients with non-small cell lung cancer.

32p trinhthamhodang7 31-08-2020 35 3   Download

Analysis of mutation and protein expression of EGFR in patients with lung adenocarcinoma. Investigation the hypermethylation frequency of EGFR, BRCA1, MGMT, MLH1, RASSF1A and correlation of the methylation between these genes with mutations and protein expression of EGFR.

27p trinhthamhodang7 31-08-2020 41 2   Download

Twenty one genotypes including check Krishna were evaluated in randomized block design with three replications during kharif-2017 at research farm of TCA, Dholi for estimation of genetic variability among them. Genotypes varied significantly for all the morpho-physiological characters indicating the presence of considerable variability among the genotypes. Significant bidirectional shift was observed in the mean values as compared to better check, thus provided scope for selection.

5p angicungduoc6 22-07-2020 19 2   Download

In order compute genetic variability, heritability and genetic advance expressed as per cent of mean, an investigation was carried out with 79 plants of F2 population of MFC-09-12 × PGCP-12 and 90 plants of F2population of MFC-08-14 × PL-3 in cowpea. Considerably high amount of variability was observed for the thirteen quantitative and qualitative characters under study.

9p nguaconbaynhay5 16-05-2020 25 1   Download

Nuclear factor erythroid-2 related factor 2 (Nrf2) is a crucial transcription factor that regulates the expression of defensive antioxidants and detoxification enzymes in cells. In a previous study, we showed that expression of the Nrf2 gene is regulated by an epigenetic modification. Rauvolfia verticillata, a traditional Chinese herbal medicine widely used in China, possesses anticancer and antioxidant effects. In this study, we investigated how Nrf2 is epigenetically regulated by reserpine, the main active component in R. verticillata, in mouse skin epidermal JB6 P+ cells.

11p caothientrangnguyen 09-05-2020 17 2   Download

Breast cancer is the most common cancer among women and the molecular pathways that play main roles in breast cancer regulation are still not completely understood. MicroRNAs (miRNAs) and transcription factors (TFs) are important regulators of gene expression.

17p nutifooddau 27-01-2019 17 3   Download

MicroRNAs (miRNAs) are small noncoding RNAs of about 19–25 nt that regulate gene expression posttranscriptionally under various cellular conditions, including apoptosis. The miRNAs involved in modulation of apoptotic events in T cells are partially known.

10p nutifooddau 27-01-2019 28 2   Download

An optogenetic upgrade for the tet - OFF system fused the inhibitor to the blue light-responsive B-LID degron and optimized the performance of this construct with regard to the number of Med25VBD repeats. This approach resulted in an optogenetic upgrade of the popular Tet-OFF (TetR-VP64, tetO7-PhCMVmin)  system  that  allows tunable, blue light-inducible gene expression in HEK-293T  cells.

5p thuyancn 01-06-2015 32 5   Download

High-Level Recombinant Protein Production in CHO Cells Using Lentiviral Vectors and the Cumate Gene-Switch developed  an efficient system to generate in less than 2 months, starting from the cDNA, pools of CHO cells stably expressing high-level of recombinant  proteins. It is based on lentiviral vectors (LVs) for stable transduction coupled with the cumate gene-switch for inducible and efficient gene expression.

13p thuyancn 01-06-2015 37 3   Download

A novel vector platform for vitamin H-inducible transgene expression in mammalian cells have therefore designed a strategy to convert antibiotic-responsive transcription factors into gene regulation systems responsive to non-toxic biotin, also known as vitamin H.

9p thuyancn 01-06-2015 45 5   Download

DNA of prokaryotes is in a nonequilibrium structural state, characterized as ÔactiveÕ DNA supercoiling. Alterations in this state a€ect many life processes and a homeostatic control of DNA supercoiling has been suggested [Menzel, R. & Gellert, M. (1983) Cell 34, 105±113]. We here report on a new method for quantifying homeostatic control of the high-energy state of in vivo DNA. The method involves making small perturbation in the expression of topoisomerase I, and measuring the e€ect on DNA supercoiling of a reporter plasmid and on the expression of DNA gyrase....

8p system191 01-06-2013 38 5   Download

The human b-globin gene locus is the subject of intense study, and over the past two decades a wealth of information has accumulated on how tissue-specific and stage-specific expression of its genes is achieved. The data are extensive and it would be difficult, if not impossible, to formulate a comprehensive model integrating every aspect of what is currently known. In this review, we introduce the fundamental characteristics of globin locus regulation as well as questions on which much of the current research is predicated.

11p system191 01-06-2013 50 4   Download

Mer belongs to the Tyro 3 family of receptor tyrosine kinases (RTKs). Together with Axl and Rse, the three RTKs are believed to play important functional roles in the male gonads because gene knockout male mice lacking all of these receptors are infertile. In the present study, postnatal expression of Axl and Rse in mouse testes decreased during maturation while expression of Mer increased age-dependently during testicular development.

12p system191 01-06-2013 46 3   Download