Integrative medicine during the intensive phase of chemotherapy in pediatric oncology in Germany: A randomized controlled trial with 5-year follow up

Integrative medicine is used frequently alongside chemotherapy treatment in pediatric oncology, but little is known about the influence on toxicity. This German, multi-centre, open-label, randomized controlled trial assessed the effects of complementary treatments on toxicity related to intensive-phase chemotherapy treatment in children aged 1–18 with the primary outcome of the toxicity sum score.