Lithium chloride promotes apoptosis in human Leu-kemia NB4 cells by inhibiting glycogen synthase Ki-nase 3-beta

Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML). With the application of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO), APL becomes one of best prognosis of leukemia.