Molecular mechanism of an aspirin compound for alleviation of osteoporosis using nerwork pharmacology and molecular docking

The aspirin compound (AC) is commonly found to have a wide range of pharmacological activities. This study aimed to investigate the underlying mechanism of the anti-osteoporotic (anti-OP) activity of AC using network pharmacology and molecular docking approaches. First, AC targets were identified using the GeneCards database, and second, OP-related targets were mined using a combination of the GeneCards and DisGeNet databases.