Novel amphiphilic pyridinium ionic liquids‑supported Schiff bases: Ultrasound assisted synthesis, molecular docking and anticancer evaluation

Pyridinium Shiff bases and ionic liquids have attracted increasing interest in medicinal chemistry. A library of 32 cationic fluorinated pyridinium hydrazone-based amphiphiles tethering fuorinated coun‑ teranions was synthesized by alkylation of 4-fuoropyridine hydrazone with various long alkyl iodide exploiting lead quaternization and metathesis strategies.