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Prognostic and predictive significance of long interspersed nucleotide element-1 methylation in advanced-stage colorectal cancer
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Hypomethylation of Long Interspersed Nucleotide Element-1 (LINE-1) is associated with worse prognosis in colorectal cancer (CRC). However, little is known about the relevance of this marker for the prognosis and response to chemotherapy of metastatic and recurrent (advanced-stage) CRC.
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