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Prognostic models for outcome prediction in patients with advanced hepatocellular carcinoma treated by systemic therapy: A systematic review and critical appraisal
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To describe and analyze the predictive models of the prognosis of patients with hepatocellular carcinoma (HCC) undergoing systemic treatment. This study describes and analyzes the prognostic models developed and validated for patients with HCC who have undergone systemic treatment. The results show that there are some methodological flaws in the model development process, and that external validation is rarely performed.
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